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TNBC

1. Triple negative breast cancer (TNBC) is a subtype of breast cancer that lacks three specific receptors: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). This means that TNBC does not respond to hormonal therapies or targeted therapies that target these receptors.


2. TNBC accounts for approximately 10-20% of all breast cancer cases. It is more commonly diagnosed in younger women, African American women, and women with a BRCA1 gene mutation.


3. TNBC tends to be more aggressive and has a higher risk of recurrence compared to other types of breast cancer. It may also have a higher likelihood of spreading to other organs, such as the lungs or brain.


4. Due to the lack of targeted therapies, chemotherapy is the primary treatment option for TNBC. This can include a combination of drugs, such as anthracyclines and taxanes.


5. Research is ongoing to identify potential targeted therapies for TNBC. Some promising areas of study include immunotherapy, PARP inhibitors, and drugs that target specific molecular pathways involved in TNBC.


6. It is important for individuals with TNBC to work closely with their healthcare team to develop a personalized treatment plan. This may include regular follow-up appointments, imaging tests, and discussions about potential clinical trials or new treatment options.

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